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Table 2 Effects of dietary supplementations of 100 ppm of ZnO without (BASAL) or with 120 ppm of apramycin (ANTIBIO), 2,500 ppm of ZnO (HIGH), and 100 ppm of the lipid-encapsulated ZnO (LE) on clinical signs of post-weaning pigs challenged with 5 × 10 8cfu of ETEC K88

From: Effects of a lipid-encapsulated zinc oxide dietary supplement, on growth parameters and intestinal morphology in weanling pigs artificially infected with enterotoxigenic Escherichia coli

Item

BASAL

ANTIBIO

HIGH

LE

SEM

P- value

Rectal temperature, °C

D 0

38.48

38.52

38.50

38.48

0.15x

 

D 1

39.85a

39.47ab

39.22b

39.57ab

 

D 4

40.08a

39.43bc

39.22c

39.63b

 

D 7

39.75a

39.32b

38.98bc

38.85c

 

Overall1

39.54a

39.18b

38.98b

39.13b

0.10

<0.01

Fecal consistency score2

D 0

1.50

1.67

1.83

1.50

  

D 1

2.83

2.67

2.33

2.50

  

D 2

2.67

2.83

2.33

2.50

0.22x

 

D 4

2.50a

2.17a

2.17a

1.50b

  

D 7

2.50a

1.83b

1.67b

1.67b

  

Overall3

2.40a

2.23ab

2.07b

1.93b

0.11

0.04

Fecal shedding of E. coli, Log10 cfu/g feces

D 1

7.00a

5.90b

5.35b

5.58b

  

D 4

6.86a

5.71b

5.22bc

4.83c

0.29x

 

D 7

7.33a

5.50b

4.91bc

4.25c

  

Overall4

7.06a

5.70b

5.16b

4.89b

0.33

<0.01

  1. 1 P-values for the day and day × treatment were < 0.01 and 0.04, respectively.
  2. 21, well-formed feces; 2, sloppy feces; 3, diarrhea.
  3. 3 P-values of the day and day × treatment were < 0.01 and 0.25, respectively.
  4. 4 P-values of the day and day × treatment were 0.09 and 0.22, respectively.
  5. xApplies to all day × treatment combinations.
  6. a-cMeans with no common superscript within a row differ (P < 0.05).