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Table 4 Effects of oral administration of the MYCI mixture on intestinal mucosal morphology of newborn piglets after an oral administration of PEDVa)

From: Medicinal herb extracts ameliorate impaired growth performance and intestinal lesion of newborn piglets challenged with the virulent porcine epidemic diarrhea virus

 

Not challenged

Challenged (Chal)

P-value

CONb) (n = 5)

MYCI (n = 5)

SEM

CON (n = 6)

MYCI (n = 6)

SEM

Chal

MYCI

C × M

Duodenum

         

VHb), μm

443

482

38.3

409

471

31.7

0.050

<0.001

0.023

CDb), μm

171

171

10.7

183

173

16.1

0.183

0.255

0.533

VH:CD

2.65

2.72

0.163

2.31

2.74

0.149

0.590

0.392

0.002

Jejunum

         

VH, μm

144

151

11.7

129

154

13.3

0.156

0.002

0.030

CD, μm

157

137

13.0

170

138

9.5

0.040

<0.001

0.001

VH:CD

0.98

1.18

0.166

0.89

1.23

0.155

0.946

0.377

0.013

Ilium

         

VH, μm

166

182

13.3

161

184

10.1

0.648

<0.001

0.015

CD, μm

165

166

15.9

160

142

11.0

0.001

0.027

0.048

VH:CD

1.12

1.16

0.156

1.01

1.32

0.170

0.933

0.547

0.058

  1. aNewborn piglets received an oral challenge with 3 × 103.5 TCID50 of PEDV in PBS or PBS only and daily administration 60 mg of the MYCI mixture suspended in milk replacer or the vehicle for 7 days
  2. bCON, control; VH, villus height; CD, crypt depth