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Table 4 Top five identified structural analogs in the Protein Data Bank (PDB) library

From: In silico characterisation, homology modelling and structure-based functional annotation of blunt snout bream (Megalobrama amblycephala) Hsp70 and Hsc70 proteins

  PDB ID Protein Species TM-score RMSDa IDENa Cov.
Ma-Hsp70 1yuwA Hsc70 Bos taurus 0.986 0.95 0.896 0.996
4j8fA Hsc70 Rattus norvegicus 0.688 1.78 0.676 0.711
3cqxB Hsc70 Mus musculus 0.678 0.90 0.902 0.685
3iucC Hsp70 Homo sapiens 0.677 0.95 0.687 0.685
3qmlA Hsp70 Saccharomyces cerevisiae 0.669 1.17 0.656 0.682
Ma-Hsc70 1yuwA Hsc70 Bos taurus 0.986 1.24 0.958 1.000
4j8fA Hsc70 Rattus norvegicus 0.688 1.81 0.654 0.711
3cqxB Hsc70 Mus musculus 0.678 0.90 0.960 0.685
3iucC Hsp70 Homo sapiens 0.677 0.95 0.698 0.685
3qmlA Hsp70 Saccharomyces cerevisiae 0.669 1.17 0.659 0.682
  1. Analogs were inferred by COFACTOR analysis, based on the TM-score of the structural alignment between the query structure and known structures in the PDB. RMSDa is the average root mean square deviation between residues that are structurally aligned by TM-align; IDENa is the percentage sequence identity in the structurally aligned region; Cov. represents the coverage of the alignment by TM-align and is equal to the number of structurally aligned residues divided by length of the query protein